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GLP-1 microdosing

Enhance your health with GLP-1s

Our personalized GLP-1 microdosing protocols are built to reduce inflammation, improve brain function, enhance heart health and raise longevity biomarkers — not to strip weight off you.

$249/month
Every formulation, one price
Get Your Custom Plan
  • Labs included (Labcorp)
  • Unlimited provider visits
  • FSA/HSA approved
  • No membership or sign-up fees
Apex MD compounded GLP-1/GIP microdose bottles: Muscle + Energy, Metabolic Support and Mind + Energy
Personalized titration Reduce inflammation Improve brain function Improve sleep Improve heart health
What microdosing is

A fraction of the dose, aimed at a different outcome

Full-dose GLP-1s are built for weight loss. Microdosing uses the same medications at a much lower dose, combined with targeted additives, to work on inflammation, energy, cognition and metabolic health while you hold your muscle.

Personalized to your labs

Blood labs are included in your program. As your body’s needs change, so does your personalized mix.

Proprietary protocols

Our protocols set the combination of GLP-1s and additives you get, every time — not a one-size dose.

One price, everything in

$249 a month covers all doses, your labs and unlimited provider visits. No membership fee, no lab fee.

Choose your delivery

Four ways to microdose

Every option is compounded with glycine and/or B-vitamins, includes your labs and unlimited provider visits, and costs the same.

Most popular
Injection · weekly

Compounded Semaglutide Microdose

Weekly self-administered shot from a pre-filled pen.

$249/mo
  • Weekly injections
  • Unlimited provider visits
  • Labs included (Labcorp)
  • Dietitian support included
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Injection · weekly

Compounded Tirzepatide Microdose

Weekly shot, dual GLP-1/GIP action.

$249/mo
  • Weekly injections
  • Unlimited provider visits
  • Labs included (Labcorp)
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Oral · daily

Semaglutide ODT Microdose

Daily dissolvable tablet. No injections.

$249/mo
  • Daily pills
  • Unlimited provider visits
  • Labs included (Labcorp)
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Oral · daily

Tirzepatide ODT Microdose

Daily dissolvable tablet, dual GLP-1/GIP action.

$249/mo
  • Daily pills
  • Unlimited provider visits
  • Labs included (Labcorp)
Get Started

Prescription products. Whether you’re a candidate, and which formulation you receive, is decided by your Apex MD provider after your labs.

Daily oral formulations

Five mixes, each aimed at one job

Your provider picks the formulation that matches what your labs and your goals call for.

Muscle & Energy

GLP-1/GIP · B-12 · NAD+

Formulated to lower inflammation, enhance recovery, and help build and maintain muscle and energy. This formula is not titrated for weight loss, but for improving overall body tone.

Metabolic Support

GLP-1/GIP · inositol · berberine

Formulated to support blood sugar, enhance insulin sensitivity, metabolic health and elevated A1C levels. May be a good fit for those who are prediabetic and want to optimize blood sugar.

Mind + Energy

GLP-1/GIP · B-12 · NAD+

Formulated to enhance focus and mood, clear brain fog, improve cognitive health and revitalize energy. For those who want optimal focus and mental health.

Sleep Support

Morning: GLP-1/GIP · NAD+ · B-12  •  Evening: GLP-1/GIP · L-theanine · magnesium

A two-part tablet formulation built to improve your sleep/wake rhythm through the day and take you deeper into REM sleep at night. For people who wake up feeling unrested and stay tired all day.

Microdose Core

GLP-1/GIP · NAD+ · inositol · methionine · choline chloride

Formulated to maintain weight-loss results, hold muscle mass and lower inflammation. Built for clients who have already hit their GLP-1 weight-loss goal and want to keep it while improving overall health.

What goes in the mix

The additives, and what each one is for

Your personalized mix can include any of these. Open one to see why it’s used alongside a GLP-1.

An Apex MD compounded GLP-1 microdose bottle
NAD+
  • Enhances cellular energy production, which can counteract the fatigue and low energy often experienced on GLP-1 medications.
  • Supports mitochondrial function and fat metabolism, potentially amplifying the weight-management effects of GLP-1 agonists.
  • Provides anti-aging and longevity benefits by promoting cellular repair and reducing oxidative stress.
  • May mitigate side effects such as muscle loss or metabolic slowdown by aiding detoxification and preserving vitality.
Vitamin B-12
  • Prevents or treats deficiency caused by reduced food intake or altered absorption, supporting energy and red blood cell formation.
  • Enhances fat metabolism and energy production, potentially boosting the efficacy of GLP-1 agonists.
  • Supports nervous system health and may reduce fatigue during GLP-1 therapy.
  • Aids in preserving lean muscle mass and motivation.
Vitamin B-6
  • Reduces nausea, a frequent GLP-1 side effect, improving tolerance and adherence.
  • Supports metabolism and energy production, potentially enhancing blood sugar control and weight loss.
  • Aids neurotransmitter synthesis, which may help manage mood and stress during treatment.
  • May improve sleep quality and cognitive function.
Magnesium
  • Supports blood sugar control and insulin sensitivity, enhancing GLP-1’s glycemic effects.
  • May alleviate constipation, a common GLP-1 side effect, by promoting bowel regularity.
  • Aids muscle and nerve function, reducing cramps or fatigue during therapy.
  • Helps manage stress and improve sleep.
Choline
  • Aids fat transport and metabolism, supporting liver health and potentially preventing fat buildup.
  • Essential for cell structure and messaging, which may help maintain metabolic function during reduced calorie intake.
  • May improve blood sugar regulation alongside GLP-1 agonists.
  • Supports DNA synthesis and nervous system health, helping mitigate nutrient deficiencies from appetite suppression.
Inositol
  • Supports fat metabolism and mood balance, potentially aiding GLP-1 effects and reducing emotional eating.
  • May improve insulin sensitivity, complementing glucose regulation.
  • Helps with PCOS-related symptoms.
  • Supports liver function and cellular health during reduced calorie intake.
Methionine
  • Supports fat breakdown and liver detoxification as part of lipotropic blends.
  • Aids in preventing excess fat buildup in the liver during rapid weight loss.
  • Contributes to energy production and may help manage fatigue.
  • Essential for protein synthesis, supporting muscle maintenance during calorie reduction.
Glycine
  • May support metabolic health and reduce inflammation.
  • Aids detoxification and liver function during fat loss.
  • Promotes better sleep and cognitive function, potentially mitigating fatigue.
  • Supports gut health and regularity.
L-theanine
  • Used in the evening formulation to support calm and deeper sleep.
  • Paired with magnesium to take you further into REM sleep.
L-carnitine
  • Supports the transport of fatty acids for energy production.
  • Used in Apex MD’s full-dose GLP-1 blends alongside NAD+ and B-12.

These are the roles each additive plays in the formulation. They are not a claim that any one ingredient treats a condition on its own, and your mix is set by your provider.

The wider view

Some of the world’s leading longevity doctors are endorsing GLP-1s for optimal health

“These medications don’t just help you shed pounds—they improve heart health and might even tackle inflammation tied to obesity.”

Dr. Mehmet Oz

“GLP-1 agonists may reduce the risk of cancer, kidney disease, and cardiovascular disease.”

Dr. Peter Attia

“My practice recommends GLP-1 agonists in the right cases as part of a broader, holistic health plan.”

Dr. Gabrielle Lyon

Physicians quoted are speaking about GLP-1 medications generally. They are not affiliated with Apex MD and these statements are not an endorsement of Apex MD or its products.

Dr. Jim Bowen, Chief Medical Officer of Apex MD
Who writes the protocols

Dr. Jim Bowen, Apex MD’s Chief Medical Officer

A Mayo Clinic–trained physician with 40+ years in optimization medicine, Dr. Bowen oversees a national network of 1,000+ providers and wrote the microdosing protocols this program runs on.

Your labs are read by a licensed provider, prescriptions are written only where your results support them, and medications are dispensed by US-based, FDA-registered 503B compounding pharmacies.

Apex MD is not urgent or emergency care. If you think you’re having a medical emergency, call 911.

Get your personalized microdosing mix

Fill out the intake form and an Apex MD provider builds your protocol around your labs. $249 a month, everything included.

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